Founder of Skylight Discovery, Inc. and Adjunct Professor at University of California San Francisco (UCSF)Inventor of the technique for measuring conformational changes - changes in structural shape - of biomolecules in real time based on a nonlinear optical technique, second-harmonic generation (SHG).Previously, I founded and was CSO at two VC-backed companies in the SF Bay Area, Quanta Therapeutics and Biodesy.Biodesy developed SHG instruments, which were acquired by Pharma, biotech companies and universities.Quanta Therapeutics is using these SHG instruments to discover and develop allosteric modulators of Ras, a protein that when mutated drives nearly 30% of all human cancers.